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Efficacy of DOTA-PRIT evaluated as tumor growth and survival in mice bearing SW1222 subcutaneous xenografts. (A) Tumor growth presented as change in tumor volume for each individual mouse over time (green, no treatment; blue, 177Lu-DOTA-Bn only; red, DOTA-PRIT; red arrows, 3-cycle treatment times). (B) Kaplan–Meier plot of DOTA-PRIT (shown as time to tumor burden of 1,000 mm3).
