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. 2017 Sep 22;18(10):2043. doi: 10.3390/ijms18102043

Figure 1.

Figure 1

Licochalcone A (Lico.A) inhibits the production of nitric oxide (NO) and prostaglandin E2 (PGE2) and expression of iNOS and COX-2 in lipopolysaccharide (LPS)-stimulated BV-2 cells. (a) NO production was measured by Griess reagents; (b) The production of PGE2 in supernatant was analyzed by ELISA; (c,d) The mRNA levels of iNOS and COX-2 were measured by RT-PCR; (f,g) The protein levels of iNOS and COX-2 were analyzed by Western blot. All the experiments were repeated at least three times and similar results were observed. Values are mean ± SE (standard error), (n = 5 samples/group). # p < 0.01 vs. NT group (cultured in medium alone); ** p < 0.01, * p < 0.05 vs. LPS group.