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Lomefloxacin induces changes in cellular red and green (JC-1) or blue (DAPI) fluorescence intensity as a result of apoptosis induction in COLO829 cells. The cells were treated with lomefloxacin at a concentration of 1.0 mmol/L for 24 h. The cells were observed under a fluorescence image cytometer (scale bar 50 µm). Q1ur—mitochondrial membrane polarized cells; Q1lr—mitochondrial membrane depolarized/apoptotic cells; M1—DAPI-positive/late apoptotic cells.
