Table 5.
Baseline cost-effectiveness based upon quality-adjusted life year (QALY) and primary outcomes: imputed data, NHS and PSS perspectivea
| Outcome Measure | Mean costs (95% CI) | Mean effects (95% CI) | Probability that gFNP is | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| gFNP (£) | Usual care (£) | Difference (£) | gFNP | Usual care | Difference | ICER (£) | More effectiveb (%) | Less costlyb (%) | Cost-effectiveb (%)# | Cost-effectiveb (%)± | Cost-effectiveb (%)∞ | |
| QALY [28] | N = 97 | N = 67 | N = 97 | N = 67 | ||||||||
| 8179 (5397, 10961) | 6107 (5029, 7184) | 2072 (− 843, 4988) | 0 · 92 (0 · 84, 1 · 00) | 0 · 93 (0 · 85, 1 · 00) | − 0 · 01 (− 0 · 05, 0 · 03) | − 247,485 (NW) | 19 · 2 | 2 · 8 | 2 · 0 | 2 · 3 | 3 · 0 | |
| AAPI-2 [22] | N = 97 | N = 67 | N = 97 | N = 67 | ||||||||
| 8179 (5903, 10455) | 6107 (5160, 7054) | 2072 (− 392, 4537) | 0 · 27 (0 · 14, 0 · 40) | 0 · 25 (0 · 12, 0 · 38) | 0 · 02 (− 0 · 17, 0 · 21) | 111,334 (NE) | 58 · 4 | 1 · 9 | 19 · 1 | 25 · 1 | 32 · 9 | |
| CARE Index maternal sensitivity [23] | N = 97 | N = 67 | N = 97 | N = 67 | ||||||||
| 8179 (5903, 10455) | 6107 (5160, 7054) | 2072 (− 392, 4537) | 3 · 97 (3 · 54, 4 · 39) | 4 · 84 (4 · 30, 5 · 38) | − 0 · 87 (− 1 · 55, − 0 · 19) | − 2382 (NW) | 1 · 2 | 1 · 4 | < 1 | < 1 | < 1 | |
a(£, 2014–2015 prices), bBased on 10,000 bootstrap replicates of the dataset
The gFNP intervention was considered to be “cost-effective” if it had positive net benefit at a: #GBP £15,000 cost-effectiveness threshold, ±GBP £20,000 cost-effectiveness threshold, ∞GBP £30,000 cost-effectiveness threshold
gFNP Group Family Nurse Partnership, GBP, pounds sterling, NHS National Health Service, PSS personal social services, CI confidence interval, ICER incremental cost-effectiveness ratio, NW north-west quadrant of cost-effectiveness plane, NE north-east quadrant of the cost-effectiveness plane, QALY quality-adjusted life years, AAPI-2 Adult-Adolescent Parenting Inventory