Table 3.

List of genes enriched or not inside the new cured gene set oxyntic mucosa tested inside the Hallmark catalogue

		Trial 1 (2-week-old piglets)		Trial 2 (3-week-old piglets)
Gene product	Gene name	Rank enrichment score^a	Core enrichment	Rank enrichment score^a	Core enrichment
Potassium voltage-gated channel, Isk-related family, member 2	KCNE2	0.729	Yes	0.330	Yes
Epidermal growth factor	EGF	0.583	Yes	0.185	Yes
Anion exchanger 2	SLC4A2	0.580	Yes	0.176	Yes
Lipoprotein lipase	LPL	0.578	Yes	0.321	Yes
Potassium inwardly rectifying channel, subfamily J, member 15	KCNJ15	0.576	Yes	0.406	Yes
Chloride intracellular channel 6	CLIC6	0.495	Yes	0.070	No
Solute carrier family 2 (facilitated glucose transporter), member 4	SLC2A4	0.479	Yes	0.275	Yes
ATPase, H⁺/K⁺ exchanging, β polypeptide	ATP4B	0.417	Yes	0.058	No
ATPase, H⁺/K⁺ exchanging, α polypeptide	ATP4A	0.371	Yes	0.013	No
Insulin-like growth factor binding protein 5	IGFBP5	0.266	Yes	0.055	No
Pheromaxein, subunit C	PHEROC	0.248	Yes	−0.048	No
Acquaporin 4	AQP4	0.236	Yes	0.006	No
Potassium inwardly rectifying channel, subfamily J, member 13	KCNJ13	0.167	No	0.202	Yes
Ghrelin	GHRL	0.094	No	−0.237	No
Trefoil factor 1	TFF1	0.093	No	0.002	No
Pepsinogen C	PGC	0.075	No	−0.072	No
Insulin-like growth factor 1	IGF1	0.067	No	0.401	Yes
Pepsinogen B	PGB	−0.023	No	−0.202	No
Chitinase, acidic	CHIA	−0.089	No	−0.121	No

^aReflects the relative degree to which a gene is overrepresented at the top (positive sign) or bottom (negative sign) of the ordered dataset