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Clinical course and changes in laboratory data. The 61‐year‐old male patient was diagnosed with severe sepsis complicated by thrombotic microangiopathy on day 3 (black arrow). Plasma exchange was applied on days 3–6 to treat the thrombotic microangiopathy and resulted in improved platelet count (PLT; square), serum creatinine level (Cr; triangle), and lactate dehydrogenase (LDH; rhombus) level.
