Table 2.

Characteristics of REasons for Geographic And Racial Difference in Stroke (REGARDS)-Medicare linked study participants ≥ 65 years of age, taking antihypertensive medication at baseline by number of indicators of frailty.

Characteristic	Number of Indicators of Frailty
	0 (n = 2,919)	1 (n = 1,391)	2 (n = 618)	≥3 (n = 308)
Age, years (SD)	72.2 (5.4)	73.4 (5.9)	74.4 (6.4)	74.0 (6.4)
Women	48.7	57.5	64.9	61.7
Black	35.0	43.7	46.5	46.1
Less than a high school education	13.0	20.4	26.1	31.8
Household income < $20,000	20.0	32.3	41.4	48.6
Region of residence  Stroke belt  Stroke buckle  Non-belt	34.2 23.3 42.5	36.0 21.9 42.1	39.4 23.0 37.6	38.1 25.4 36.6
Current smoker	7.3	10.3	11.4	12.0
Mean SBP, mmHg	132.2 (16.3)	133.3 (18.8)	133.4 (18.2)	134.1 (19.1)
Mean DBP, mmHg	76.0 (9.5)	75.8 (9.6)	75.8 (10.1)	75.2 (10.8)
Classes of antihypertensive medications	2 (1–3)	2 (1–3)	2 (2–3)	2 (2–3)
Coronary heart disease	26.2	31.2	33.8	44.5
Stroke	6.6	12.1	19.7	29.5
Diabetes	25.1	30.2	39.1	45.5
ACR, mg/g	12.6 (12.0–13.2)	15.4 (14.2–16.7)	19.6 (17.2–22.3)	19.2 (16.1–22.9)
Osteoporosis medication use	8.1	9.3	9.1	7.6
Benzodiazepine use	5.5	7.3	12.1	14.2
Statin use	45.3	45.5	43.6	46.1
Indicators of frailty
Low BMI	0.0	1.9	1.9	2.7
Cognitive impairment	0.0	21.6	26.0	38.4
Depressive symptoms	0.0	11.2	29.3	60.4
Exhaustion	0.0	19.2	55.7	82.3
Impaired mobility	0.0	34.7	60.6	82.9
History of falls	0.0	11.6	26.5	52.4

Numbers in this table are percentage or mean (standard deviation) except for ACR, which is the geometric mean (95% confidence interval) and number of antihypertensive medications is the median (interquartile range).

ACR: Urine Albumin to Creatinine Ratio; BMI: Body mass index; DBP: Diastolic Blood Pressure; SBP: Systolic Blood Pressure.