Figure 1.
Non-amyloidogenic and amyloidogenic pathways in AD neurons. In the amyloidogenic pathway the APP is aberrantly spliced by BACE1 and γ-secretase to overproduce toxic Aβ species.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.