Skip to main content
. 2017 Sep 20;7(16):4057–4070. doi: 10.7150/thno.20151

Figure 7.

Figure 7

Serological antibody response induced by the BCG vaccine in guinea pigs. (A) Discovery of antibody hits using M-NAPPA TB proteome microarrays using the sera pool from guinea pigs immunized with the BCG vaccine (n=4) or PBS (negative control, n=5); (B) The four top hits with increased antibody signal in guinea pigs vaccinated with BCG; (C) Deconvolution and verification of antigens using RAPID-ELISA and individual guinea pig sera. The p-value was calculated using an un-paired Man Whitney t-test. * p-value ≤0.01, ** p-value ≤0.001, *** p-value ≤0.001; (D) Annotation of identified TB antigens associated with the BCG vaccine.