Fig. 3.

Experiment 3: Light exposure under normoxia when pretreament with lutein - Secretion levels of angiogenin, bFGF, and VEGF from supernatant with or without a blue light filter. Trends in the secretion of angiogenin, bFGF, and VEGF following lutein pretreatment were similar to those observed when RPE cells were grown under hypoxic and normoxic conditions; however, none of the trends were found to be significant. A slight increase in angiogenin levels was seen when RPE cells were exposed to white light with a BLF; however, this result was not found to be significant. In addition, decreases in light-induced bFGF and VEGF secretion were observed with blue light filtering; however, these decreases were also insignificant. (NS: non significant; * = P ≤ 0.05; ** ≤0.01)