Figure 5.
Assessment of HBPE-S PNP’s cellular uptake and cytotoxicity using fluorescence microscopy. A–C) Minimal internalization was observed with carboxylated NPs (7), whereas, D–F) enhanced internalization was observed with folate NPs. G–I) A549 cells were incubated with taxol encapsulating folate NPs (9), leading to mitotic arrest and cell death. Nuclei stained with DAPI dye (blue).