Table 1.
Baseline Characteristics of Pairs of Patients With Cancer and Matched Controls, 2002–2011, Stratified by Cancer Type
| Characteristic | All Cancer Cohorts (N = 279,719) |
Breast Cohort (N = 62,977) |
Lung Cohort (N = 56,941) |
Prostate Cohort (N = 64,164) |
Colorectal Cohort (N = 43,827) |
Bladder Cohort (N = 17,637) |
NHL Cohort (N = 15,669) |
Pancreas Cohort (N = 12,279) |
Gastric Cohort (N = 6,225) |
|---|---|---|---|---|---|---|---|---|---|
| Age, mean ± SD, yrs | 75 ± 7 | 75 ± 7 | 75 ± 7 | 74 ± 6 | 77 ± 7 | 77 ± 7 | 76 ± 7 | 77 ± 7 | 77 ± 7 |
| Sex | |||||||||
| Women | 146,729 (52) | 62,608 (99) | 31,226 (55) | 0 (0) | 26,446 (60) | 6,062 (34) | 9,505 (61) | 7,794 (63) | 3,088 (50) |
| Men | 132,990 (48) | 369 (1) | 25,715 (45) | 64,164 (100) | 17,381 (40) | 11,575 (66) | 6,164 (39) | 4,485 (37) | 3,137 (50) |
| Race | |||||||||
| White | 238,094 (85) | 55,685 (88) | 48,676 (85) | 52,393 (82) | 36,960 (84) | 16,063 (91) | 13,977 (89) | 10,040 (82) | 4,300 (69) |
| Nonwhite | 41,625 (15) | 7,292 (12) | 8,265 (15) | 11,771 (18) | 6,867 (16) | 1,574 (9) | 1,692 (11) | 2,239 (18) | 1,925 (31) |
| Geographic region | |||||||||
| Northeast | 53,409 (19) | 12,580 (20) | 9,954 (17) | 11,618 (18) | 8,880 (20) | 3,776 (21) | 3,062 (20) | 2,357 (19) | 1,182 (19) |
| Midwest | 47,207 (17) | 10,411 (17) | 9,085 (16) | 11,275 (18) | 7,799 (18) | 2,926 (17) | 2,843 (18) | 1,966 (16) | 902 (14) |
| South | 72,352 (26) | 15,339 (24) | 17,311 (30) | 15,768 (25) | 11,615 (27) | 4,127 (23) | 3,689 (24) | 3,081 (25) | 1,422 (23) |
| West | 106,751 (38) | 24,647 (39) | 20,591 (36) | 25,503 (40) | 15,533 (35) | 6,808 (39) | 6,075 (39) | 4,875 (40) | 2,719 (44) |
| Charlson comorbidities | |||||||||
| 0 | 209,973 (75) | 49,312 (78) | 37,350 (66) | 52,958 (83) | 33,023 (75) | 13,129 (74) | 11,694 (75) | 8,171 (67) | 4,336 (70) |
| 1 or more | 69,746 (25) | 13,665 (22) | 19,591 (34) | 11,206 (17) | 10,804 (25) | 4,508 (26) | 3,975 (25) | 4,108 (33) | 1,889 (30) |
| HTN or AF | 170,880 (61) | 41,422 (66) | 34,033 (60) | 35,268 (55) | 27,439 (63) | 10,753 (61) | 9,749 (62) | 8,259 (67) | 3,957 (64) |
| Census tract poverty level <10%* | 151,621 (54) | 36,409 (58) | 28,069 (49) | 35,465 (55) | 23,027 (53) | 10,118 (57) | 8,991 (57) | 6,501 (53) | 3,041 (49) |
| Cancer stagef | |||||||||
| 0 | 20,089 (7) | 10,193 (16) | 39 (0) | 22 (0) | 2,826 (6) | 6,926 (39) | NA | 24 (0) | 59 (1) |
| 1 | 85,539 (31) | 25,842 (41) | 8,474 (15) | 31,444 (49) | 8,708 (20) | 5,370 (30) | 3,915 (25) | 651 (5) | 1,135 (18) |
| 2 | 60,964 (22) | 15,333 (24) | 2,025 (4) | 26,226 (41) | 10,855 (25) | 1,958 (11) | 2,145 (14) | 1,977 (16) | 445 (7) |
| 3 | 33,811 (12) | 4,587 (7) | 13,567 (24) | 1,566 (2) | 9,595 (22) | 876 (5) | 2,414 (15) | 729 (6) | 477 (8) |
| 4 | 51,309 (18) | 3,337 (5) | 24,733 (43) | 2,035 (3) | 8,134 (19) | 1,414 (8) | 5,339 (34) | 4,629 (38) | 1,688 (27) |
| Unknown | 28,007 (10) | 3,685 (6) | 8,103 (14) | 2,871 (5) | 3,709 (8) | 1,093 (6) | 1,856 (12) | 4,269 (35) | 2,421 (39) |
Data presented as number (%) unless otherwise specified. Total numbers represent the total number of matched pairs. Cancer patients and matched controls without cancer had equal values for age, sex, race, geographic region, Charlson comorbidities, and hypertension or atrial fibrillation. Due to rounding, some values do not add to 100.
Number and proportion of patients who live in areas where less than 10% of people are below the poverty line according to the 2000 census. †Refers to the American Joint Committee on Cancer (AJCC) staging schema, except for patients with prostate cancer, who were staged according to the T (clinical) staging classification and patients with NHL, who were staged according to the Ann Arbor staging classification. Cancers diagnosed from 2002 through 2003 were staged according to the AJCC third edition definitions, whereas cancers diagnosed from 2004 through 2011 were staged according to the sixth edition. There is a higher proportion of patients with pancreatic and gastric cancer with an unknown stage because AJCC staging before 2004 is not available in SEER for these patients.
AF = atrial fibrillation; HTN = hypertension; NA = not applicable; NHL = non-Hodgkin lymphoma