Table 3. Multivariable analysis of clinical and cardiac dose-volume variables associated with PCE development in prospective and retrospective patient groups.

Variable	Prospective Group		Retrospective Group
	HR (95% CI)	P Value*	HR (95% CI)	P Value*
HV35
>10% vs. <10≤	2.14 (1.31-3.51)	0.002	1.52 (1.05-2.21)	0.027
Age, years
≥70 vs. <70	0.67 (0.40-1.12)	0.127	0.93 (0.61-1.42)	0.741
Tumor Location
Right vs. Left	0.52 (0.33-0.81)	0.004	1.14 (0.79-1.66)	0.477
Adjuvant Chemotherapy
Yes vs. No	2.82 (1.72-4.65)	<0.001	1.40 (0.93-2.09)	0.108
Cardiac History
Yes vs. No	1.68 (1.09-2.60)	0.020	0.81 (0.56-1.18)	0.278

Abbreviations: HR, hazard ratio; CI, confidence interval.

^*Cox proportional hazards model