Skip to main content
. 2017 Nov 2;12(11):e0187434. doi: 10.1371/journal.pone.0187434

Table 1. Physiological parameters and blood tests.

Parameters Sham Control Control+Ex4 DM DM+Ex4
Body mass gained (g)* - +2.1±23 +11.1±9.9 -27.5±11.5 -18.0±7.5
Gastric pH 4.1±0.5 3.3±1.2 3.3±0.5 3.0±0.9 2.9±0.5
Blood glucose (mg/dl)# 166.2±33.9 153.5±22.5 121.5±12.1 329.6±125.5 381.0±104.0
Serum IL-6 (pg/ml) 35.5±11.5 46.2±11.9 - 36.7±13.7 52.6±46
Serum MCP-1 (pg/ml) 70.3±30.7 90.0±59.4 - 138.5±101.8 115.8±82.3

DM: diabetes mellitus; Ex4: exendin-4; IL-6: interleukin-6; MCP-1: monocyte chemotactic protein-1;

*Body mass (BM) change = BM at induction of peptic ulcer—BM at sacrifice.

#Blood glucose levels were measured at the end of experiment (at sacrifice).

P< 0.05 compared with control (statistical analysis was performed with sham group). Serum concentrations of IL-6 and MCP-1 were not measured in control+Ex4 group. Data was analyzed by one-way ANOVA. n = 8–9 in control, control+Ex4, DM and DM+Ex4 groups, n = 4 in sham.