Skip to main content
. 2017 Nov 2;12(11):e0187510. doi: 10.1371/journal.pone.0187510

Table 2. Positive predictive value of ICD-10-GM by code group, and number of inpatient events.

Code group Level N PPV 95%-CI Hospital-acquired events [%]
1: N99.0—Postprocedural renal failure 1: Disease 54/54 100.0 (93.4,100) 41/54 [75.9]
2: ADE 37/54 68.5 (54.4,80.5) 30/37 [81.1]
2: D69.52/53—Sec. thrombocytopenia: Heparin-induced type I/II 1: Disease 48/54 88.9 (77.4,95.8) 23/48 [47.9]
2: ADE 38/54 70.4 (56.4,82.0) 22/38 [57.9]
3: L27.1—Localized skin eruption due to drugs and medicaments 1: Disease 51/56 91.1 (80.4,97.0) 36/51 [70.6]
2: ADE 47/56 83.9 (71.7,92.4) 34/47 [72.3]
4: F19.2/7—Mental and behavioral disorders due to multiple drug use and use of other psychoactive substances 1: Disease 48/54 88.9 (77.4,95.8) 1/48 [2.1]
2: ADE 10/54 18.5 (9.3,31.4) 1/10 [10.0]
5: F11.2/7—Mental and behavioral disorders due to use of opioids 1: Disease 53/54 98.1 (90.1,100) 0/53 [0]
2: ADE 3/54 5.6 (1.2,15.4) 0/3 [0]
6: G62.0—Drug-induced polyneuropathy 1: Disease 48/54 88.9 (77.4,95.8) 1/48 [2.1]
2: ADE 46/54 85.2 (72.9,93.4) 1/46 [2.2]
7: M81.4—Drug-induced osteoporosis 1: Disease 44/54 81.5 (68.6,90.8) 0/44 [0]
2: ADE 35/54 64.8 (50.6,77.3) 0/35 [0]
8: F13.2/7—Mental and behavioral disorders due to use of sedatives or hypnotics 1: Disease 41/48 85.4 (72.2,93.9) 2/41 [4.9]
2: ADE 24/48 50.0 (35.2,64.8) 2/24 [8.3]
9: K52.1—Toxic gastroenteritis and colitis 1: Disease 52/54 96.3 (87.3,100) 28/52 [53.8]
2: ADE 45/54 83.3 (70.7,92.1) 26/45 [57.8]
10: L27.0—Generalized skin eruption due to drugs and medicaments 1: Disease 53/54 98.1 (90.1,100) 41/53 [77.4]
2: ADE 51/54 94.4 (84.6,98.8) 41/51 [80.4]
11: I95.2—Hypotension due to drugs 1: Disease 50/54 92.6 (82.1,98.0) 28/50 [56.0]
2: ADE 39/54 72.2 (58.4,83.5) 25/39 [64.1]
12: D61.1—Drug-induced aplastic anemia 1: Disease 41/54 75.9 (62.4,86.5) 3/41 [7.3]
2: ADE 40/54 74.1 (60.3,85.0) 3/40 [7.5]
13: D70.1—Drug-induced agranulocytosis and neutropenia 1: Disease 48/54 88.9 (77.4,95.8) 17/48 [35.4]
2: ADE 46/54 85.2 (72.9,93.4) 17/46 [37.0]
14: A04.7—Enterocolitis due to Clostridium difficile 1: Disease 53/54 98.1 (90.1,100) 31/53 [58.5]
2: ADE 37/54 68.5 (54.4,80.5) 26/37 [70.3]
15: D69.57/58/59—Other secondary thrombocytopenia 1: Disease 52/55 94.5 (84.9,98.9) 5/52 [9.6]
2: ADE 27/55 49.1 (35.4,62.9) 3/27 [11.1]
Total 1: Disease 736/807 91.2 (89.0,93.1) 257/736 [34.9]
2: ADE 525/807 65.1 (61.7,68.3) 231/525 [44.0]