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High-grade muscle-invasive bladder cancer induced by BBN treatment at 20 weeks. (A) H&E, 40×; (B) gold enhanced, 40×; (C) H&E, 100×; (D) gold enhanced, 100×; (E) gold enhanced, 200×; (F) gold enhanced region of bladder wall devoid of tumor, 100×.
Abbreviations: BBN, N-butyl-N-(4-hydroxybutyl)nitrosamine; H&E, hematoxylin and eosin; T, tumor; S, stroma.
