Table 2. ESBL and MLST characterization results of cohort study.
| Time points of weekly sample collection | |||
|---|---|---|---|
| CatID a | T1 | T2 | T3 |
| C1 | CTX-M-1 (1); CTX-M-1 + TEM-1b (1); CMY-2 (2) | N | N |
| C2 | N | CTX-M-32 (1) | N |
| C3 | CTX-M-1 (4) | N | N |
| C4-C17 | N | N | N |
| E1 | N | CTX-M-1 (3) | SHV-12 (2); CMY-2 + TEM-1b (2) |
| E2 | CTX-M-1 (ST410) (2); CTX-M-2 + TEM-1b (1) | CTX-M-1 (ST410) (2) | CTX-M-1 (ST410) (2); CTX-M-32 (2) |
| E3 | CTX-M-1 (3) | N | N |
| E4 | CMY-2 (ST38) (2) | CTX-M-15 + TEM-1b (3) | CMY-2 (ST38) (3) |
| E5 | N | N | CTX-M-1 (1); SHV-12 (2) |
| E6 | N | CTX-M-1 (ST3381) (1); CTX-M-32 (1); SHV-12 (ST1850) (1) | CTX-M-1 (ST2607) (1); CTX-M-1 + TEM-1d (3); SHV-12 (ST2067) (1) |
| E7 | CTX-M-1 + TEM-1b (ST58) (2) | CTX-M-1 + TEM-1b (ST58) (3) | CTX-M-1 + TEM-1b (ST58) (1) |
| E8 | N | N | N |
| E9 | N | N | CTX-M-1 (2); CMY-2 (1) |
| E10 | N | CTX-M-14 (1) | CTX-M-1 + TEM-1b (3) |
| E11 | CTX-M-2 + TEM-1b (3) | N | N |
| E12 | CTX-M-1 + TEM-1b (ST69 and ST117) b (3) | CTX-M-1 + TEM-1b (ST69) (3) | CTX-M-1 + TEM-1b (ST69) (3) |
| E13 | TEM-52c (3) | CTX-M-24 + TEM-1d (2); CMY-2 (1) | CTX-M-1 (2) |
| E14 | N | CTX-M-1 (ST155) (1); CTX-M-1 + TEM-1b (1); CTX-M-32 (2); CTX-M-32 + TEM-1b (1); TEM-52c (Unknown ST) (1) | CTX-M-1 (ST398) (1); SHV-12 (1); TEM-52c (ST1284) (1) |
| E15 | CMY-2 (1) | N | CTX-M-1 (1) |
| E16 | CTX-M-1 (ST117) (2); CMY-2 (2) | N | CTX-M-1 (ST117) (1) |
| E17 | CTX-M-1 + TEM-1b + OXA-1 (1); CTX-M-1 + TEM-1 + TEM-1b (Unknown ST) (1); CMY-2 (1) | CTX-M-1 (3) | CTX-M-1 + TEM-1 + TEM-1b (Unknown ST) (2); CTX-M-15 + TEM-1b + TEM-var c (1) |
| E18 | CTX-M-1 (3); CMY-2 + TEM-32 (1) | CMY-2 (3) | SHV-12 (3) |
| E19 | N | N | N |
a CatID: C(x) is cat in control group, E(x) is cat in exposed group. N, fecal sample without growth on MCC. Isolates with different ESBL types in one sample are separated by a semicolon. Number of isolates with ESBL type is given in brackets. E. coli ST is given when similar ESBL types were found in consecutive samples (underlined genes).
b The same gene combination was found in two E. coli isolates with distinct STs obtained from the same fecal sample. c TEM-1var is a TEM-1 protein with an identical nucleotide sequence as deposited at GenBank GU371927.