Table 3. Differences between children with esophagitis and children with normal endoscopy.

	Children with esophagitis (n = 31)	Children without esophagitis (n = 88)	p
Age, mean (range)	11.0 (0.25–18)	7.11 (0.17–18)	<0.001
Gender (male/female)	19/12	47/41	0.448
pH-metry alone
Reflux episodes, mean (range)	43.7 (0–101)	35.8 (1–114)	0.198
Reflux index, %, mean (range)	29.9 (0–80.5)	11.7 (0–85.7)	<0.001
Multiple intraluminal impedance
Number of total reflux episodes, mean (range)	91.6 (1–197)	78.0 (5–246)	0.193
Number of acidic reflux episodes, mean (range)	78.0 (0–192)	57.2 (1–242)	0.036
Number of weakly acidic reflux episodes, mean (range)	13.3 (0–92)	19.6 (0–79)	0.105
Number of non-acidic reflux episodes, mean (range)	0.2 (0–2)	0.8 (0–16)	0.198
Bolus elimination time, s, mean (range)	6.1 (0–39.2)	3.8 (0.3–18)	0.023
% of proximal reflux episodes	45.7 (0–84.6)	52.7 (0–100)	0.313
DeMeester composite reflux score	95.5 (0.8–239.6)	37.9 (0.8–235.7)	<0.001
Boix-Ochoa composite reflux score	83.8 (1–187.4)	36.0 (1–213.9)	<0.001
SI %, mean (range)	59.2 (0–100)	50.6 (0–100)	0.170
SSI % mean (range)	6.2 (0–22)	12.1 (0–85)	0.034
SAP % mean (range)	67.3 (0–100)	70.1 (0–100)	0.695
Number of children with GERD determined by pH, n (%)	25 (80.6%)	37 (42%)	<0.001
Number of children with GERD determined by MII, n (%)	8 (25.8%)	32 (36.4%)	0.378
Number of children with GERD determined by pH-MII, n (%)	27 (87.1%)	55 (62.5%)	0.013

SI- symptom index; SSI- symptom sensitivity index; SAP- symptom association probability.