Table 4. Relationship between latent class trajectory, sociodemographic, clinical factors and functioning overtime.
| Moderately stable vs High | Deterioration vs High | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | p value | |
| Positive symptoms | ||||||
| Early response and stable | Ref | Ref | ||||
| Delayed response | 2.80 | (1.9,4.12) | <0.001 | 3.46 | (1.53,7.84) | 0.003 |
| Negative symptoms | ||||||
| Early response and stable | Ref | Ref | ||||
| Early response and relapse | 4.57 | (2.54,8.22) | <0.001 | 3.41 | (1.21,9.59) | 0.020 |
| Delayed response | 2.42 | (0.42,14.08) | 0.324 | 9.18 | (1.07,79.08) | 0.044 |
| Slower response and no response | 1.00 | (0.66,1.54) | 0.987 | 0.84 | (0.27,2.59) | 0.762 |
| General psychopathology symptoms | ||||||
| Early response and stable | Ref | Ref | ||||
| Early response and relapse | 22.02 | (9.88,49.07) | <0.001 | 227.21 | (76.32,676.42) | <0.001 |
| Delayed response* | . | . | ||||
| Slower response and no response | 2.73 | (1.78,4.17) | <0.001 | 5.87 | (1.82,18.96) | 0.003 |
| Age | 0.99 | (0.97,1.01) | 0.258 | 0.98 | (0.92,1.05) | 0.571 |
| Gender | ||||||
| Male vs Female | 1.18 | (0.93,1.51) | 0.168 | 1.97 | (0.96,4.07) | 0.065 |
| Marital status | ||||||
| Married vs. single | 0.84 | (0.58,1.21) | 0.352 | 1.57 | (0.54,4.57) | 0.412 |
| Separated/divorced vs. single | 1.12 | (0.62,2.04) | 0.707 | 0.94 | (0.1,8.69) | 0.960 |
| Employment status | ||||||
| Unemployed vs. Employed | 1.36 | (1.02,1.81) | 0.038 | 1.63 | (0.64,4.17) | 0.305 |
| Economically inactive vs. Employed | 0.83 | (0.58,1.17) | 0.282 | 1.12 | (0.39,3.23) | 0.838 |
| Ethnicity | ||||||
| Malay vs. Chinese | 0.92 | (0.66,1.29) | 0.638 | 1.63 | (0.69,3.87) | 0.268 |
| Indian vs. Chinese | 0.79 | (0.49,1.28) | 0.345 | 0.84 | (0.25,2.9) | 0.788 |
| Others vs. Chinese | 0.85 | (0.39,1.83) | 0.670 | 1.26 | (0.21,7.4) | 0.799 |
| Education | ||||||
| Primary vs. Tertiary | 1.14 | (0.8,1.64) | 0.465 | 1.23 | (0.49,3.09) | 0.665 |
| Secondary vs. Tertiary | 1.26 | (0.97,1.63) | 0.078 | 0.93 | (0.44,1.97) | 0.854 |
| DUP symptoms | 1.01 | (1,1.01) | 0.028 | 1.01 | (1,1.02) | 0.140 |
| SCID Diagnoses | ||||||
| Affective psychosis vs. Schizophrenia spectrum & delusional disorder | 0.82 | (0.53,1.27) | 0.375 | 0.48 | (0.1,2.36) | 0.370 |
| Brief psychotic disorder & psychotic disorder NOS vs. Schizophrenia spectrum & delusional disorder | 0.69 | (0.49,0.98) | 0.037 | 0.77 | (0.25,2.38) | 0.651 |
Note: High functioning is reference group.
* = Parameter estimates were not estimated due to low number