Fig 5. A section of a multiple sequence alignment of M49 peptidases.

Thirty M49 peptidases were selected from different eukaryotic and bacterial species. The active-site motifs I and II as well as ETGE motif are framed. The loop between the two conserved active-site motifs of the human M49 peptidase is highlighted in grey. The full names of the species are given in S2 Table.