Figure 4. Constitutive Trpm5 mRNA expression increases experimental pulmonary metastasis through tail vein injection of B16-BL6 cells.

Representative clones of cells transfected with empty vector (control) and Trpm5-expressing vector (Trpm5) were grown individually, pooled and injected into tail veins of mice. (A) Photograph of a lung 3 weeks after injection. (B) Metastasized foci at the lung surface. Data are represented as mean ± SE (n = 15). ***P < 0.01.