Table 2. Relationship between clinicopathological factors and exosomal miR-203 expression in serum in CRC.
| Variables | Low (n=119) number (%) |
High (n=121) number (%) |
P |
|---|---|---|---|
| Sex | 0.81 | ||
| Female | 47 (39.5) | 46 (38.0) | |
| Male | 72 (60.5) | 75 (62.0) | |
| Tumor size (cm) | 0.59 | ||
| <5 | 70 (58.8) | 67 (55.4) | |
| ≧5 | 49 (41.2) | 54 (44.6) | |
| Histology | 0.81 | ||
| Well | 71 (59.7) | 74 (61.2) | |
| Not Well | 48 (40.3) | 47 (38.8) | |
| Depth of invasion | 0.11 | ||
| ≦MPa | 46 (38.7) | 34 (28.1) | |
| ≧SSb | 73 (61.3) | 87 (71.9) | |
| Venous invasion | 0.02 | ||
| (-) | 54 (45.4) | 37 (30.6) | |
| (+) | 65 (54.6) | 84 (69.4) | |
| Lymphatic invasion | 0.06 | ||
| (-) | 82 (68.9) | 69 (57.0) | |
| (+) | 37 (31.1) | 52 (43.0) | |
| Lymph node metastasis | <0.01 | ||
| (-) | 77 (64.7) | 56 (46.3) | |
| (+) | 42 (35.3) | 65 (53.7) | |
| Distant metastasis | <0.01 | ||
| (-) | 97 (81.5) | 78 (64.5) | |
| (+) | 22 (18.5) | 43 (35.5) | |
| Liver metastasis | <0.01 | ||
| (-) | 115 (96.6) | 79 (65.3) | |
| (+) | 4 (3.4) | 42 (34.7) | |
| Lung metastasis | 0.04 | ||
| (-) | 114 (95.8) | 107 (88.4) | |
| (+) | 5 (4.2) | 14 (11.6) | |
| Peritoneal dissemination | 0.05 | ||
| (-) | 108 (90.8) | 117 (96.7) | |
| (+) | 11 (9.2) | 4 (3.3) | |
| Others | 0.10 | ||
| (-) | 117 (98.3) | 113 (93.4) | |
| (+) | 2 (1.7) | 8 (6.6) | |
| TNM Stage | <0.01 | ||
| I, II | 68 (57.1) | 37 (30.6) | |
| III, IV | 51 (42.9) | 84 (69.4) |
Correlation was analyzed by Fisher’s exact test.
aMP, muscularis propria; bSS, subserosa.