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. 2017 Aug 10;8(45):78614–78632. doi: 10.18632/oncotarget.20201

Figure 8. β1-integrin recycling appears to be under LRP-1 dependence in thyroid tumor cells.

Figure 8

FTC-133 cells were plated onto 1% gelatin coated coverslips, maintained under control conditions (CTRL) or 500 nM RAP treatment (+RAP), and then stained with Alexa Fluor 488 for Rab11 (left panels) and Alexa Fluor 568 for active β1-integrin (9EG7, upper panel) or inactive β1-integrin (Mab13, lower panel) before confocal microscopy analysis. Colocalization between Rab11 and either active or inactive β1-integrin is represented in yellow (colocalized pixels: right panel). 2-fold enlargements (insets) are indicated by full and empty white arrowheads. Bars: 10 μm.