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. 2017 Sep 5;8(45):78948–78964. doi: 10.18632/oncotarget.20695

Figure 3. The EBV immediate early gene BRLF1 induces genomic instability.

Figure 3

(A) TW01 cells were transiently transfected with the doses (μg) of pRTS15 for 24 h and micronucleus formation assay was performed. Data are presented as means ± SD. **, P < 0.01, compared to mock. (B) TW01 cells were transiently transfected with pRTS15 for 24, 48 and 72 h. Western blotting and (C) micronucleus formation assay were performed. Data are presented as means ± SD. **, P < 0.01, compared to mock treatment at the same time point. (D) TW01-TetER cells were treated with 50 ng/ml Dox for 24 h andmicronucleus formation assay was performed. Data are presented as means ± SD. **, P < 0.01, compared to TW01-TetER mock treatment. (E) 293-TetER cells were treated with 50 ng/ml Dox for 24 h andmicronucleus formation assay was performed. Data are presented as means ± SD. *, P < 0.05, compared to 293-TetER mock treatment.