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. 2017 Aug 24;8(45):78965–78977. doi: 10.18632/oncotarget.20697

Figure 4. CTC are detected at diagnosis and decrease in response to therapy.

Figure 4

(A) CTC and CTC clusters were quantified from blood samples drawn from patients with the indicated diagnoses. ES = Ewing sarcoma, OS = osteosarcoma, Chondro = chondrosarcoma, SS = synovial sarcoma, DSRCT = desmoplastic small round cell tumor, MLS = myxoid liposarcoma, ERMS = embryonal rhabdomyosarcoma, and ARMS = alveolar rhabdomyosarcoma. (B) CTC and clusters were quantified from blood samples obtained from patients with the indicated diagnoses at a time when the patient had no radiographic evidence of disease. (C) CTC and CTC clusters were quantified from blood samples drawn from patients at various time points in their therapy. For graphing purposes, each cluster was considered to have 4 cells. Red lines and symbols represent patients who subsequently relapsed, and green lines and symbols represent patients who remain without radiographic evidence of disease.