Table 1. Summary of H3K27 regulators expression in the developing human cerebellum.
Week 9 GSA | Week 28 GSA | Week 33 GSA | Week 40 GSA | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
URL | EGL | VZ | LRL | EGL | ML | PCL | IGL | EGL | ML | PCL | IGL | EGL | ML | PCL | IGL | |
EZH2 | +++ | +++ | +++ | +++ | + | - | - | +/- | + | - | - | - | - | - | - | - |
KDM6A | +++ | ++ | +++ | +++ | + | - | ++ | +/- | - | - | - | - | - | - | - | - |
KDM6B | ++ | ++ | +++ | ++ | - | - | ++ | +/- | - | - | +++ | +/- | - | - | +++ | +/- |
H3K27me3 | +++ | +++ | +++ | +++ | + | +/- | + | + | + | +/- | ++ | + | +/- | - | +/- | + |
URL, upper rhombic lip; EGL, external granule layer; VZ, ventricular zone; LRL, lower rhombic lip; ML, molecular layer; PCL, Purkinje cell layer; IGL, internal granule layer. Relative staining intensity is indicated as: - absent staining; + / - weak and sporadic staining; + low intensity staining or strong sporadic staining; ++ medium intensity staining; +++ high intensity staining.