Table 2. Correlation of cripto-1 protein expression with clinicopathological parameters.
| Characteristics | Cripto-1(low) | Cripto-1(high) | P value |
|---|---|---|---|
| Age (years) | |||
| ≥58 | 69 | 78 | |
| <58 | 64 | 79 | 0.709 |
| Sex | |||
| female | 78 | 80 | |
| male | 55 | 77 | 0.190 |
| Smoking status | |||
| yes | 51 | 68 | |
| no | 82 | 89 | 0.392 |
| Tumour location | |||
| left | 53 | 72 | |
| right | 80 | 85 | 0.303 |
| Lesion type | |||
| central | 57 | 75 | |
| peripheral | 76 | 82 | 0.402 |
| pT status | |||
| T1 | 80 | 78 | |
| T2+T3+T4 | 38 | 62 | 0.047 |
| pN status | |||
| N0 | 77 | 56 | |
| N1+N2+N3 | 48 | 92 | <0.001 |
| pM status | |||
| M0 | 111 | 137 | |
| M1 | 22 | 20 | 0.359 |
| pTNM status | |||
| I+II | 80 | 64 | |
| III+IV | 53 | 93 | 0.001 |
| EGFR mutation status | |||
| yes | 65 | 66 | |
| no | 68 | 91 | 0.244 |
| Serum CEA | |||
| normal (≤5 ng/mL) | 79 | 80 | |
| elevated (>5ng/mL) | 54 | 77 | 0.150 |
| E-cadherin | |||
| negative | 63 | 105 | |
| positive | 70 | 52 | 0.001 |