Table 4. Effectors of preoperative hypopituitarism revealed by logistic regression analysis.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Age, years | ||||
| ≤ 37 | Reference | Reference | ||
| 38-49 | 4.93 (1.33, 18.31) | .017 | 4.23 (1.06, 16.82) | .041 |
| > 49 | 4.31 (1.18, 15.81) | .027 | 3.25 (0.83, 12.74) | .091 |
| Male gender | 5.59 (1.94, 16.08) | .001 | 4.88 (1.64, 14.55) | .004 |
| Type of adenoma | ||||
| Gonadotropin | Reference | |||
| Prolactin | 1.3 (0.31, 5.39) | .718 | ||
| Null-cell | 1.56 (0.42, 5.85) | .510 | ||
| Others1 | 1.6 (0.41, 6.21) | .497 | ||
| NFPA adenoma | 1.49 (0.58, 3.83) | .408 | ||
| Tumor size, mm | 1.14 (0.66, 1.98) | .634 | ||
| Tumor volume, mm3 | 1.01 (1, 1.02) | .090 | ||
| Level of resection | ||||
| Complete | 0.56 (0.15, 2.14) | .399 | ||
| Massive | 0.64 (0.15, 2.77) | .550 | ||
| Partial | Reference | |||
| Grade of cavernous sinus invasion | 0.78 (0.47, 1.29) | .326 | ||
| Grade of suprasellar extension | 1.07 (0.66, 1.74) | .771 | ||
| Total score of invasion | 1 (0.8, 1.24) | .972 | ||
| Cystic degeneration | 1.06 (0.42, 2.67) | .907 | ||
Abbreviations: OR: odds ratio; CI: confidence interval; NFPA: non-functioning pituitary adenomas