Table 3. Tumor response in two groups.

Outcome	Raltitrexed group N = 40	Control group N = 46	P value*
Disease control rate	16	14	0.353
Complete response	0	1
Partial response	1	1
Stable disease	15	12
Progressive disease	22	31
Not evaluated†	1	2

*P value was calculated by a two-sided χ2 test. † There were 3 patients who could not be evaluated for treatment response beacause of death, poor performance status, or patients’ refusal of evaluation at 4-6 weeks.