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. 2017 Mar 25;8(45):79175–79187. doi: 10.18632/oncotarget.16577

Table 2A. Drug-related adverse events by maximum grade per patient (N = 28).

Adverse Event Grade 1 Grade 2 Grade 3 Grade 4 Grade 3/4 (%)
Hematology
Lymphocytopenia 10 (36%) 3 (11%) 6 (21%) 0 21%
White Blood Count 8 (29%) 7 (25%) 7 (25%) 1 (4%) 29%
Neutropenia 1 (4%) 7 (25%) 8 (29%) 2 (7%) 36%
Thrombocytopenia 14 (50%) 3 (11%) 0 3 (11%) 11%
Anemia 9 (32%) 10 (36%) 3 (11%) 0 11%
Gastrointestinal disorders
Nausea 11 (39%) 1 (4%) 0 0 0%
Vomiting 3 (11%) 1 (4%) 0 0 0%
Gastroesophageal reflux disease 4 (14%) 0 0 0 0%
Constipation 2 (7%) 0 0 0 0%
Diarrhea 2 (7%) 0 0 0 0%
Chemistry
Hyponatremia 3 (11%) 0 1 (4%) 0 4%
Hypomagnesemia 1 (4%) 0 0 0 0%
Increased AST 4 (14%) 1 (4%) 1 (4%) 0 4%
Increased ALT 4 (14%) 0 0 0 0%
Other
Fatigue 8 (29%) 5 (18%) 0 0 0%
Carboplatin allergic reaction 0 0 0 0 0%
Skin rash 3 (11%) 1 (4%) 0 0 0%
Weight Loss 1 (4%) 0 0 0 0%
Headache 5 (18%) 0 0 0 0%