Table 4. Hazard ratios and 95% confidence intervals of dementia risk associated with acupuncture/Tuina treatment among the migraine patients.
| No. of events | Person- years | IR | Crude HR | Adjusted HR¶ | Crude HR | Adjusted HR¶ | |
|---|---|---|---|---|---|---|---|
| (95% CI) | (95% CI) | (95% CI) | (95% CI) | ||||
| Non-TCM users | 66 | 7797 | 8.46 | 1 (reference) | 1 (reference) | - | - |
| TCM users | |||||||
| Only CHPs | 34 | 4237 | 8.03 | 0.96 (0.63–1.45) | 0.60 (0.39–0.92)* | 1.47 (0.90–2.40) | 1.01(0.61–1.68) |
| Only acupuncture/Tuina | 4 | 130 | 30.76 | 3.61 (1.31–9.90)* | 2.19 (0.79–6.12) | 5.62 (1.97–15.98)** | 4.46(1.52–13.08)** |
| Combined CHPs and acupuncture/Tuina | 30 | 5453 | 5.5 | 0.68 (0.44–1.05) | 0.62 (0.40–0.97)* | 1 (reference) | 1 (reference) |
Abbreviations: CHPs, Chinese herbal products; CI, confidence interval; HR, hazard ratio; IR, incidence rates, per 1,000 person-years; TCM, traditional Chinese medicine. ¶Adjusted HR represents adjusted hazard ratio; mutually adjusted for age, sex, diabetes mellitus, hypertension, coronary artery disease, head injury, depression, hyperlipidemia, stroke, mental disorders, chronic kidney disease, and renal dialysis in the Cox proportional hazards regression.
*P < 0.05; **P < 0.01.