Table 3. The univariate and multivariate regression analysis to identify prognostic factors for RFS.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| RFS | ||||
| Age | 0.993 (0.975–1.010) | 0.398 | - | - |
| Gender | 1.592 (0.769–3.295) | 0.210 | - | - |
| Operative time | 1.001 (0.999–1.004) | 0.308 | - | - |
| Operative procedure | 1.104 (0.722–1.686) | 0.649 | - | - |
| Operative method | 1.108 (0.731–1.679) | 0.629 | - | - |
| Blood loss | 1.000 (1.000–1.001) | 0.011 | - | - |
| Surgical margin | 0.955 (0.621–1.469) | 0.834 | 0.548 (0.343–0.875) | 0.012 |
| Tumor size | 1.616 (1.085–1.243) | < 0.001 | - | - |
| Number of tumors | 1.116 (0.539–2.309) | 0.768 | - | - |
| Differentiation | 1.118 (0.802–1.557) | 0.512 | - | - |
| MVI classification | 5.389 (3.382–8.585) | < 0.001 | 5.907 (3.543–9.848) | < 0.001 |
| Envelope invasion | 3.032 (1.568–5.863) | 0.001 | 2.868 (1.442–5.704) | 0.003 |
| Cirrhosis | 1.362 (0.551–3.368) | 0.503 | - | - |
| Viral hepatitis | 1.478 (0.785–2.783) | 0.226 | - | - |
| AFP level | 1.813 (1.369–2.402) | < 0.001 | - | - |
| Postoperative Treatment strategy | 0.004 | < 0.001 | ||
| TACE | 0.865 (0.534–1.402) | 0.557 | 0.633 (0.385–1.041) | 0.072 |
| RT | 0.416 (0.243–0.711) | 0.001 | 0.278 (0.154–0.501) | < 0.001 |