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. 2017 Apr 5;8(45):80029–80038. doi: 10.18632/oncotarget.16852

Table 4. Risk factors of postoperative morbidity.

Variable Postoperative morbidity Univariate analysis P Multivariate analysis
No(n = 561) Yes(n = 131) OR 95%CI P
Age 60.7 ± 10.1 62.8 ± 9.9 0.030 1.016 0.135
Gender 0.135
 Male 438(78.1) 70(84.0)
 Female 123(21.9) 18(16.0)
BMI(kg/m2) 22.0 ± 2.6 21.8 ± 2.5 0.201
Tumor Location 0.422
 Upper 302(53.8) 77(58.8)
 Middle 227(40.5) 45(34.4)
Total 32(5.7) 9(6.9)
Operative approach 0.009 0.596 0.009
 LATG 294(52.4) 52(39.7)
 OTG 267(47.6) 79(60.3)
Tumor size(cm) 6.1 ± 2.9 5.7 ± 2.6 0.191
pT stage 0.270
 T1 51(9.1) 17(13.0)
 T2 44(7.8) 6(4.6)
 T3 99(17.7) 27(20.6)
 T4a 367(65.4) 81(61.8)
pN stage 0.423
 N0 127 (22.6) 32(24.4)
 N1 83(14.8) 26(19.8)
 N2 95(16.9) 22(16.8)
 N3a 146(26.0) 33(25.2)
 N3b 110(19.6) 18(13.7)
pTNM stage 0.402
 IA 48(8.6) 11(8.4)
 IB 27(4.8) 11(6.4)
 IIA 30(5.3) 5(3.8)
 IIB 62(11.1) 18(13.7)
 IIIA 72(12.8) 18(13.7)
 IIIB 108(19.3) 29(22.1)
 IIIC 214(38.1) 39(29.8)
No. of comorbidities 0.023 1.527 0.035
 0 418(73.7) 82(62.6)
 1–2 138(25.6) 47(35.9)
 ≥ 3 5(0.9) 2(1.5)
No. of retrieved lymph nodes 30.9 ± 10.7 29.6 ± 10.2 0.212
Operative time (min) 241.8 ± 71.5 252.9 ± 83.3 0.121
Estimated blood loss (ml) 144.5 ± 155.8 171.1v193.0 0.094

OR: odds ratio; CI: confidence interval