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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Cancer Res. 2017 Aug 30;77(21):5808–5819. doi: 10.1158/0008-5472.CAN-16-2524

Figure 2. GA-hMSC-derived exosomes enhance GSC proliferation and clonogenicity in vitro.

Figure 2

(A, B) Proliferation assay demonstrating a significant dose-dependent increase in GSC proliferation with the addition of matched (A) and un-matched (B) GA-hMSC-derived exosomes. * p<0.01, ** p<0.001, paired t-test (C, D) Clonogenicity assay demonstrating a significant (*p< 0.05) increase in GSC neurosphere formation with the addition of matched (C) and un-matched (D) GA-hMSC-derived exosomes. In un-matched experiments GSC-7-2 was treated with exosomes and ED-CM from GA-hMSC-247 and GSC-11 was treated with exosomes and ED-CM from GA-hMSC-230. ED-CM: exosome depleted-conditioned media. See also Figure S2.