Table 1.
History of Normotensive Pregnancy (N = 40) | History of Preeclampsia (N = 40) | P-value | |||
---|---|---|---|---|---|
| |||||
Current Hypertension (N = 8) | No Current Hypertension (N = 32) | Current Hypertension (N = 24) | No Current Hypertension (N = 16) | ||
| |||||
median (IQR) | median (IQR) | median (IQR) | median (IQR) | ||
| |||||
Age at MRI (years) | 62 (59, 66) | 59 (56, 62) | 60 (58, 63) | 57 (54, 60) | 0.05 |
Age at menopause (years) | 50 (46, 50) | 50 (48, 53) | 50 (48, 54) | 50 (49, 51) | 0.78 |
Education (years) | 14 (13, 16) | 14 (13, 16) | 14 (12, 15) | 14 (13, 16) | 0.70 |
Mean systolic blood pressure (mm Hg) | 160 (131, 164) | 123 (114, 138) | 137 (130, 143) | 123 (119, 134) | 0.004 |
Mean diastolic blood pressure (mm Hg) | 82 (76, 86) | 74 (69, 80) | 80 (72, 87) | 78 (69, 82) | 0.17 |
Hypertension duration (years) | 7 (5, 11) | 13 (8, 14) | |||
Body mass index (kg/m2) | 24.2 (22.9, 27.6) | 25.6 (23.2, 32.6) | 32.0 (28.5, 34.5) | 26.1 (23.8, 31.4) | 0.02 |
| |||||
n (%) | n (%) | n (%) | n (%) | ||
| |||||
Menopausal hormone therapy use | 4 (50) | 13 (41) | 10 (42) | 7 (44) | 0.97 |
Migraine | 3 (38) | 5 (16) | 6 (25) | 3 (19) | 0.54 |
Dementia | 0 (0) | 0 (0) | 1 (4) | 0 (0) | |
Hyperlipidemia | 6 (75) | 23 (72) | 19 (79) | 13 (81) | 0.92 |
Diabetes | 0 (0) | 2 (6) | 4 (17) | 0 (0) | 0.29 |
Severe Preeclampsia | -- | -- | 3 (12) | 4 (25) | 0.41* |
Results from Fisher’s Exact test between two groups with history of Preeclampsia only
Significant p-value shows that within each pregnancy group, mean SBP was greater in women with current hypertension than without hypertension (P<0.02). Non-significant p-values indicate that none of the four groups differed on those characteristics.
Abbreviations: MRI: magnetic resonance imaging; WMH: white matter hyperintensity.