Skip to main content
. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Biopharm Drug Dispos. 2017 Aug 22;38(8):449–457. doi: 10.1002/bdd.2085

Fig. 1.

Fig. 1

Sgk1 stimulates hOAT3 transport activity. COS-7 cells were co-transfected with hOAT3 and control vector, with hOAT3 and wild type sgk1 (WT-sgk1), with hOAT3 and constitutive active form of sgk1 (CA-sgk1), or with hOAT3 and inactive sgk1 (IN-sgk1). 3-min uptake of [3H]-estrone sulfate (0.3 μM) was then determined. The data represented uptake into hOAT3-transfected cells minus uptake into mock cells (parental COS-7 cells). Uptake activity was expressed as a percentage of the uptake measured in control cells. Values are mean ± S.E. (n = 3).