Skip to main content
. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Biopharm Drug Dispos. 2017 Aug 22;38(8):449–457. doi: 10.1002/bdd.2085

Fig. 3.

Fig. 3

Effect of sgk1 on the kinetics of hOAT3-mediated estrone sulfate transport. COS-7 cells were co-transfected with hOAT3 and control vector or with hOAT3 and the constitutive active form of sgk1 (CA-sgk1). 3-min uptake of [3H] estrone sulfate was then determined at the concentrations of 0.1–10 μM. The data represented uptake into hOAT3-transfected cells minus uptake into mock cells (parental COS-7 cells). Values are means ± S.E. (n = 3). V, velocity; S, substrate concentration.