Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 2;7:14893. doi: 10.1038/s41598-017-14194-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Biophysical and structural characterization of the p60-MIT:p80-CTD complex by AUC and X-ray crystallography. (A) Cartoon representation of the crystal structure of the p60-MIT L40P:p80-CTD complex. Blue, p60-MIT; red, p80-CTD. Microcephaly-associated mutations S538L, L543R and G581D, are highlighted as grey sticks. The intradomain hydrogen bond formed between S538 and R508 is indicated by a black dotted line. (B) c(S) distribution analysis of the p60-MIT:p80-CTD complex.