Table 3.
Gene Set Category | Total # of entities | # of measured entities | Median change | P-value | |
---|---|---|---|---|---|
Ariadne Cell Process Pathways | Adherens Junction Assembly (Nectin) | 104 | 57 | 1.10 | 0.045 |
Tight Junction Assembly (Claudins) | 137 | 62 | 1.13 | 0.022 | |
Adherens Junction Assembly (Cadherins) | 133 | 53 | 1.14 | 0.016 | |
Tight Junction Assembly (JAMs) | 119 | 55 | 1.17 | 0.024 | |
Ariadne Cell Signaling Pathways | Actin Cytoskeleton Regulation | 551 | 357 | 1.10 | 0.009 |
T Cell Activation | 957 | 490 | 1.11 | 0.003 | |
Ariadne Receptor Signaling Pathways | IL6R - > STAT signaling | 8 | 8 | 1.08 | 0.047 |
EphrinR - > actin signaling | 216 | 143 | 1.12 | 0.020 | |
T-cell receptor - > NF-kB signaling | 176 | 33 | 1.15 | 0.000 | |
T-cell receptor - > AP-1 signaling | 180 | 33 | 1.17 | 0.025 | |
T-cell receptor - > CREBBP signaling | 176 | 25 | 1.19 | 0.027 | |
GlucagonR - > CREB/ELK-SRF/SP1 signaling | 42 | 27 | 1.20 | 0.040 | |
DopamineR1 - > CREB/ELK-SRF signaling | 40 | 25 | 1.20 | 0.016 | |
T-cell receptor - > ATF/CREB signaling | 195 | 45 | 1.21 | 0.021 | |
TNFR - > CREB/ELK-SRF signaling | 45 | 30 | 1.23 | 0.050 | |
TNFRSF1A - > CREB/ELK-SRF signaling | 41 | 32 | 1.23 | 0.014 | |
NCAM1 - > CREB/ELK-SRF/MYC signaling | 27 | 21 | 1.26 | 0.046 |
Only those pathways with a median fold-change greater than 5% are presented. The number of measured entities in the pathway is reported along with the number of measured entities and median fold-change for the pathway.