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. 2017 Nov 2;7:14930. doi: 10.1038/s41598-017-14930-8

Table 3.

Gene set enrichment analysis (GSEA) for transcripts in Carassius auratus RGC cultures treated with 1000 nM SN (P < 0.05).

Gene Set Category Total # of entities # of measured entities Median change P-value
Ariadne Cell Process Pathways Adherens Junction Assembly (Nectin) 104 57 1.10 0.045
Tight Junction Assembly (Claudins) 137 62 1.13 0.022
Adherens Junction Assembly (Cadherins) 133 53 1.14 0.016
Tight Junction Assembly (JAMs) 119 55 1.17 0.024
Ariadne Cell Signaling Pathways Actin Cytoskeleton Regulation 551 357 1.10 0.009
T Cell Activation 957 490 1.11 0.003
Ariadne Receptor Signaling Pathways IL6R - > STAT signaling 8 8 1.08 0.047
EphrinR - > actin signaling 216 143 1.12 0.020
T-cell receptor - > NF-kB signaling 176 33 1.15 0.000
T-cell receptor - > AP-1 signaling 180 33 1.17 0.025
T-cell receptor - > CREBBP signaling 176 25 1.19 0.027
GlucagonR - > CREB/ELK-SRF/SP1 signaling 42 27 1.20 0.040
DopamineR1 - > CREB/ELK-SRF signaling 40 25 1.20 0.016
T-cell receptor - > ATF/CREB signaling 195 45 1.21 0.021
TNFR - > CREB/ELK-SRF signaling 45 30 1.23 0.050
TNFRSF1A - > CREB/ELK-SRF signaling 41 32 1.23 0.014
NCAM1 - > CREB/ELK-SRF/MYC signaling 27 21 1.26 0.046

Only those pathways with a median fold-change greater than 5% are presented. The number of measured entities in the pathway is reported along with the number of measured entities and median fold-change for the pathway.