Table 1.
Baseline values and effects of nitrite or saline infusions.
| Baseline | 20 min post Saline/Nitrite | ||||
|---|---|---|---|---|---|
| Saline group | Nitrite group | Saline group | Nitrite group | ||
| Arterial blood pressure | mmHg | 90.1 ± 3.6 | 93.8 ± 2.9 | 90.6 ± 3.7 | 93.5 ± 3.4 |
| Renal blood flow | mL min−1 | 4.5 ± 0.3 | 4.7 ± 0.3 | 4.5 ± 0.2 | 4.6 ± 0.3 |
| Hindquarter blood flow | mL min−1 | 8.9 ± 1.0 | 8.9 ± 0.9 | 8.7 ± 1.0 | 8.4 ± 0.9 |
| Renal vascular conductance | mL min−1 mmHg−1 | 0.051 ± 0.004 | 0.051 ± 0.004 | 0.050 ± 0.003 | 0.049 ± 0.004 |
| Hindquarter vascular cond. | mL min−1 mmHg−1 | 0.101 ± 0.013 | 0.094 ± 0.013 | 0.098 ± 0.012 | 0.093 ± 0.012 |
| Cortical tissue pO2 | mmHg | 21.4 ± 3.6 | 23.9 ± 3.4 | 22.5 ± 3.5 | 22.7 ± 3.3 |
| Medullary tissue pO2 | mmHg | 16.4 ± 3.2 | 17.6 ± 2.7 | 17.4 ± 2.9 | 17.4 ± 3.7 |
| Cortical laser flux | % change | 2.0 ± 3.3 | −3.3 ± 3.5 | ||
| Medullary laser flux | % change | 1.3 ± 5.8 | 3.0 ± 6.4 | ||
Data are mean ± SEM, n = 9 for the saline group (control), n = 11 for the nitrite group. There were no significant differences between the groups at baseline and after 20 min of nitrite or saline infusion; neither nitrite nor saline infusion resulted in significant changes vs. the respective baseline values. Please note that data on cortical and medullary laser flux are given as percentage change from baseline only, because laser fluxmetry does not provide absolute data on blood perfusion.