Table 3.
Correlation between 18F-FDG uptake and clinical disease activity
18F-FDG uptake | Correlation coefficient |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Systemic score |
ESR |
CRP |
Ferritin |
Leukocyte |
Neutrophil |
|||||||
r | p value | r | p value | r | p value | r | p value | r | p value | r | p value | |
Visual grade of lymph node | 0.664 | 0.013 | 0.462 | 0.112 | 0.265 | 0.382 | 0.338 | 0.259 | 0.091 | 0.767 | –0.009 | 0.976 |
SUV intensity of lymph node | 0.601 | 0.03 | 0.431 | 0.141 | 0.281 | 0.353 | 0.334 | 0.264 | 0.15 | 0.626 | 0.036 | 0.907 |
Visual grade of spleen | 0.771 | 0.002 | 0.617 | 0.025 | 0.527 | 0.064 | 0.557 | 0.048 | 0.499 | 0.083 | 0.469 | 0.106 |
SUV intensity of spleen | 0.676 | 0.011 | 0.456 | 0.118 | 0.512 | 0.073 | 0.477 | 0.1 | 0.499 | 0.082 | 0.413 | 0.16 |
Visual grade of bone marrow | 0.734 | 0.004 | 0.761 | 0.003 | 0.395 | 0.182 | 0.363 | 0.222 | 0.775 | 0.002 | 0.711 | 0.006 |
SUV intensity of bone marrow | 0.57 | 0.042 | 0.612 | 0.026 | 0.401 | 0.174 | 0.313 | 0.297 | 0.773 | 0.002 | 0.725 | 0.005 |
These data were assessed using a Spearman correlation. Systemic score by Pouchot et al. [3] assigns a score from 0 to 12 and adds 1 point for each of the following manifestations: fever, typical rash, pleuritis, pneumonia, pericarditis, hepatomegaly or abnormal liver function tests, splenomegaly, lymphadenopathy, leukocytosis ≥15,000/mm2, sore throat, myalgia, and abdominal pain.
18F-FDG, 18F-fluorodeoxyglucose; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; SUV, standardized uptake value.