Table 2.
Regional changes of area under the curve (AUC) values (SUV × min) for [11C]DAC at the control, acute (SE1D), subacute (SE1W) and chronic (SE3W) time points.
| Regions | AUC values (mean ± s.d.) | |||
|---|---|---|---|---|
| Control (post 3 weeks)a | Acute (SE1D)b | Subacute (SE1W)b | Chronic (SE3W)b | |
| Cerebral cortex | 21.8 ± 1.8 | 18.8 ± 0.8 | 29.3 ± 2.4*** | 29.7 ± 1.8*** |
| Striatum | 17.0 ± 1.6 | 16.0 ± 0.8 | 27.4 ± 1.4 *** | 26.3 ± 2.8*** |
| Thalamus | 17.7 ± 1.1 | 15.6 ± 0.5 | 25.8 ± 2.1*** | 29.3 ± 3.3*** |
| Hippocampus | 17.1 ± 1.1 | 16.9 ± 0.8 | 28.0 ± 2.2*** | 28.0 ± 2.3*** |
| Amygdala | 19.7 ± 1.4 | 22.6 ± 2.2 | 38.6 ± 4.8*** | 39.3 ± 5.8*** |
| Cerebellum | 23.2 ± 3.5 | 19.7 ± 0.5 | 21.9 ± 1.4 | 24.8 ± 1.9 |
| Pons | 23.4 ± 3.2 | 22.2 ± 0.8 | 22.5 ± 0.4 | 23.7 ± 2.4 |
an = 3; bn = 4.
***P < 0.001 (two-way analysis of variance with post hoc tests, compared with the control group).