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. 2017 Jun 29;123(4):757–763. doi: 10.1152/japplphysiol.00368.2017

Fig. 1.

Fig. 1.

Acute (A) and chronic (B) study designs. A: rats in acute exercise (EX) groups underwent 2 wk of treadmill training, followed by 72 h of rest. These rats were euthanized, 3–72 h after completion of a single bout of exercise (EX3h, EX12, EX24, EX48, EX72) and were compared with a control, treadmill-trained group (CA-T). A single, nontreadmill-trained group maintained normal cage activity for the duration (CA24). B: rats in chronic exercise groups underwent 2 wk of treadmill training, followed by repeated exercise sessions for 3 days or 1, 2, or 8 wk (EX3d, EX1, EX2, EX8) and were compared with either an early time point CA group (CA2) or a later time point CA group (CA8). Assays were performed on supraspinatus tendon. M, mechanics; H, histology; MMP, MMP activity assay.