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. 2017 Aug 28;8(6):706–709. doi: 10.1111/1759-7714.12494

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© 2017 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Histologic findings of the transbronchial biopsy of the lung tumor. (a) Cancer cell nest and fascicular invasion of squamous‐cell carcinoma (arrows) are seen in the stroma (hematoxylin & eosin stain, original magnification 200×). Immunohistochemical analysis revealed that (b) 10% of the cancer cells (arrowheads) were heterogeneously positive for programmed cell death ligand 1 (PD‐L1) (SP142 clone stain, original magnification 200×) and (c) tumor‐infiltrating mononuclear cells expressing programmed cell death‐1 (PD‐1) are scattered in the stroma (arrows) and within the tumor (arrowheads; SP269 clone stain, original magnification 400×).