Skip to main content
. 2017 Aug 23;8(6):582–591. doi: 10.1111/1759-7714.12487

Figure 2.

Figure 2

CRALA is not required for chemoresistant cell survival. (a) CRALA expression was determined using quantitative real time (qRT)‐PCR in parental MDA‐MB‐231 and chemoresistant breast cancer cell lines. (b) The knockdown efficiency of two specific small interfering RNAs (siRNAs) against CRALA was examined by qRT‐PCR in chemoresistant breast cancer cell lines. (c) The chemoresistant cells MDA‐MB‐231P and MDA‐MB‐231Cis were transfected with specific siRNA against CRALA or negative control (NC) for 24, 48, and 72 hours in the absence of any chemotherapeutic drug. (d) Apoptosis was determined by flow cytometry after transfection of siRNAs for 48 hours. **P < 0.01, ***P < 0.001.