Table 2.
Epac1, PDE4, and PKC protein expression in esophageal carcinoma and their correlation with clinical and pathological parameters
| Protein | Differentiation (%) | N | Lymph node (%) | N | ||||
|---|---|---|---|---|---|---|---|---|
| High | Moderate | Low | Positive | Negative | ||||
| EPAC1 | Negative | 8 (42.1) | 9 (34.6) | 2 (33.3) | 19 | 8 (34.8) | 11 (40.7) | 19 |
| Positive | 11 (57.9) | 17 (65.4) | 4 (66.7) | 32 | 15 (65.2) | 16 (59.3) | 31 | |
| χ2 | 0.308 | 0.187 | ||||||
| P | 0.857 | 0.665 | ||||||
| PKC | Negative | 6 (31.6) | 9 (33.3) | 1 (20.0) | 16 | 8 (34.8) | 8 (29.6) | 16 |
| Positive | 13 (68.4) | 18 (66.7) | 4 (80.0) | 35 | 15 (65.2) | 19 (70.4) | 34 | |
| χ2 | 0.349 | 0.152 | ||||||
| P | 0.84 | 0.697 | ||||||
| PDE4 | Negative | 5 (38.5) | 10 (50.0) | 2 (50.0) | 17 | 6 (35.3) | 11 (57.9) | 17 |
| Positive | 8 (61.5) | 10 (50.0) | 2 (50.0) | 20 | 11(64.7) | 8 (42.1) | 19 | |
| χ2 | 0.452 | 1.839 | ||||||
| P | 0.798 | 0.175 | ||||||