Fig. 5.

Abundance of intrinsic disorder in human nuclear proteins. JRONN vs. PONDR^® VSL2B plot representing the correlation between the disorder content evaluated by PONDR^® VSL2B (x-axis) [40], [41] and by JRONN (y-axis) [42]. Solid black line corresponds to the diagonal. Dashed line shows linear fit of all the data point to the equation (R²=0.90):.$D{S}_{JRONN}=–{1.4}_{\pm 1}+{0.85}_{\pm 0.02}\times D{S}_{PONDR}.$

Following the accepted practice, two arbitrary cutoffs for the levels of intrinsic disorder are used to classify proteins as highly ordered (IDP score<10% light blue field), moderately disordered (10%≤IDP score<30%, light yellow field) and highly disordered (IDP score≥30%, light pink field) [48].