Table 3.

Functions shared by highly disordered proteins.

Type	Description	Count	% avg disorder
PROCESS	Negative regulation of apoptotic process	7	77
PROCESS	Small molecule metabolic process	9	72
PROCESS	Mitotic nuclear envelope disassembly	8	72
PROCESS	Regulation of glucose transport	8	72
PROCESS	Transmembrane transport	8	72
PROCESS	Carbohydrate metabolic process	8	72
PROCESS	Glucose transport	8	72
PROCESS	Hexose transport	8	72
PROCESS	Cytokine-mediated signaling pathway	9	68
PROCESS	Mitotic cell cycle	15	66
PROCESS	Negative regulation of transcription from RNA polymerase II promoter	16	65
PROCESS	mRNA transport	9	64
PROCESS	mRNA processing	11	63
PROCESS	Negative regulation of transcription, DNA-templated	21	62
PROCESS	Transcription from RNA polymerase II promoter	11	62
PROCESS	Positive regulation of transcription from RNA polymerase II promoter	18	61
PROCESS	Transcription, DNA-templated	35	61
PROCESS	Viral process	17	60
PROCESS	Gene expression	18	60
PROCESS	RNA splicing	16	60
PROCESS	mRNA metabolic process	7	58
PROCESS	Positive regulation of transcription, DNA-templated	14	57
PROCESS	mRNA splicing, via spliceosome	11	56
PROCESS	Negative regulation of cell proliferation	7	56
PROCESS	RNA metabolic process	9	53
PROCESS	Regulation of transcription, DNA-templated	17	53
PROCESS	Negative regulation of cell growth	7	52
PROCESS	Cellular response to DNA damage stimulus	10	51
PROCESS	DNA repair	11	51
PROCESS	Cellular protein metabolic process	7	47
FUNCTION	Sequence-specific DNA binding transcription factor activity	11	65
FUNCTION	Chromatin binding	22	65
FUNCTION	DNA binding	33	63
FUNCTION	Transcription corepressor activity	10	61
FUNCTION	Poly(A) RNA binding	48	61
FUNCTION	Sequence-specific DNA binding	8	61
FUNCTION	Protein binding	91	59
FUNCTION	Enzyme binding	7	59
FUNCTION	Nucleotide binding	16	58
FUNCTION	Zinc ion binding	18	55
FUNCTION	Identical protein binding	11	55
FUNCTION	RNA binding	24	53
FUNCTION	Transcription coactivator activity	7	50
FUNCTION	ATP binding	17	50
FUNCTION	Metal ion binding	7	41