Table 2.
Effects of sex and UCP1 ablation blood lipids
Females |
Males |
|||
---|---|---|---|---|
Variable | WT | UCP1 KO | WT | UCP1 KO |
Total cholesterol, mg/dl | 50.4 ± 1.5 | 41.1 ± 1.9 | 64.6 ± 2.2* | 73.0 ± 4.4*‡ |
HDLc, mg/dl | 28.5 ± 1.0 | 22.9 ± 1.1 | 37.4 ± 1.3* | 40.2 ± 2.4*‡ |
LDLc, mg/dl | 3.6 ± 0.3 | 3.0 ± 0.1 | 2.4 ± 0.1* | 2.5 ± 0.1* |
Triglycerides, mg/dl | 134.8 ± 8.8 | 131.3 ± 4.3 | 146.4 ± 5.7 | 143.0 ± 5.1 |
NEFA, mmol/l | 0.63 ± 0.04 | 0.68 ± 0.04† | 0.56 ± 0.03 | 0.63 ± 0.03† |
Values are means ± SE.
P < 0.05, main effect of sex;
P < 0.05, main effect of genotype;
P < 0.05, sex × genotype interaction.