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Intermittent fidgeting and increases in lower limb blood flow prevent prolonged sitting-induced leg endothelial dysfunction. Popliteal artery flow-mediated dilation (FMD) measures were performed in the supine position in both legs before and after sitting for 3 h during which time one leg was subjected to intermittent fidgeting (1 min on/4 min off). n = 11. *P < 0.05 vs. before; †P < 0.05 between legs. [Modified from Morishima et al. (46).]
